The benefits are evident

Review our clinical studies to learn how embrace works beneath the surface of the skin.

Clinical studies and market research

Clinical Study

Worldwide Injection Technique Questionnaire Study: Injecting Complications and the Role of the Professional

0.55% lower A1C in those without lipohypertrophy (LH) – experts agree this is significant. 44% of Patients still inject into affected area due to habit, less pain, and convenience.

Clinical Study

Prevalence and risk factors of lipohypertrophy in insulin-injecting patients with diabetes

64% of insulin users suffer from LH. 49.1% of patients with LH had glycemic variability (GV), 7 times higher than those without. GV causes patients to use more insulin; up to 36.5% more 39.1% of patients with LH had unexplained hypoglycemia, 6 times higher than those without.

Clinical Study

Prevalence and risk factors of lipohypertrophy in insulin-injecting patients with diabetes

64% of insulin users suffer from LH. 49.1% of patients with LH had glycemic variability (GV), 7 times higher than those without. GV causes patients to use more insulin; up to 36.5% more 39.1% of patients with LH had unexplained hypoglycemia, 6 times higher than those without.

Clinical Study

Insulin Injection Into Lipohypertrophic Tissue: Blunted and More Variable Insulin Absorption and Action and Impaired Postprandial Glucose Control

Blood glucose was significantly higher when injecting into LH tissue compared to normal tissue. Insulin absorption variability increased as much as 5x when injecting into LH.

Clinical Study

Improving Cutaneous Scar by Controlling the Mechanical Environment

Mechanical compressive force reduces scarring at and below the surface of the skin by reducing expression of TGF-β1.

Clinical Study

Compressive Force Inhibits Adipogenesis Through COX-2-Mediated Down-Regulation of PPARγ2 and C/EBPα

Mechanical compressive force reduces new fat tissue growth and reduces fat cell size, the two main hallmarks of LH tissue.

Clinical Study

Mechanical Compressive Force Inhibits Adipogenesis of Adipose Stem Cells

Mechanical compressive force reduces new fat tissue growth.

Clinical Study

Tension Offloading Prevents Chronic Fibrosis Resulting From Repeated Bleomycin Injections In A Large Animal Model

Mechanical compressive force reduces inflammation in the dermis and subcutaneous tissue that leads to fibrotic scarring and LH.

Market Research

Internal Neodyne study

Survey showing high interest in the embrace® device as a way to prevent and recover scarring and LH to preserve preferred injection or insertion sites and improve diabetes management.

Learn more about the clinical science and engineering behind embrace

Clinical Science